Progetti di ricerca sul cancro presso il Weizmann Institute of Science
In questa sezione sono riportati tutti i progetti di ricerca sul cancro in corso al Weizmann Institute of Science, associati alle borse di studio che assegna il Sergio Lombroso Program.
Il vincitore della borsa di studio si unirà ad uno dei team di ricerca già al lavoro presso il Weizmann Institute of Science.
Using special flow chambers that simulate blood flow and intravital microscopy in genetically manipulated mice, Prof. Alon and his team are investigating how both endothelial and perivascular trafficking molecules promote...
The Alon lab focuses on understanding the protein circuits that perform computations within the cell.
Dr. Amit studies the genomic code enabling immune cells to differentiate into specific subtypes and devise a specific response to invading pathogens.
Prof. Kimchi’s lab is studying programmed cell death by proceeding from single-gene studies to a global network analysis.
Dr. Krizhanovsky is working to uncover the mechanisms of interaction of the senescent cells with their microenvironment, in order to understand the role of cellular senescence in tissue damage, cancer, and aging.
Prof. Lapidot and his team are primarily focused on the activities and regulation of blood-forming (hematopoietic) stem cells.
The long- term goal of Prof. Lev’s studies is to define the signaling pathways and the intracellular signaling components that contribute to the development and progression of breast cancer.
Prof. Livneh’s laboratory investigates the molecular mechanisms of DNA repair and mutagenesis and their biological role under normal and pathological conditions, primarily cancer.
Prof. Neeman’s research centers on elucidating the mechanisms that regulate angiogenesis, using magnetic resonance and optical imaging.
The main goals of Prof. Oren are to elucidate the processes that underlie the ability of p53 to act as a tumor suppressor and the mechanistic links between regulation of gene expression and cancer.
Research in Prof. Rotter’s lab is focused on revealing the mechanism by which wild-type p53 acts in normal cells and the way in which mutant p53 contributes to cancer development.
Prof. Sagi and her lab focus on the cell microenvironment which includes the extracellular matrix.
Prof. Samuel’s group aims to discover recurrent tumor-specific mutations in melanoma using high- throughput, whole-exome, and whole-genome sequencing approaches.
Dr. Shouval and her group aim to elucidate the mechanisms by which tumors reprogram their local environments.
Prof. Segal’s group develops computational models aimed at understanding how molecular components interact to carry out complex biological functions.
Prof. Seger’s current studies focus on the mechanism by which the linear signaling cascades induce many distinct, and even opposing, physiological and pathological processes.
The Shachar lab follows Lymphoid homeostasis events during health and disease, focusing on three key areas...
The Straussman group studies different mechanisms which render cancer cells resistant to chemotherapy.
Dr. Amos Tanay’s group is studying the physical interfaces that associate genomic information with mechanisms that interpret it in the nucleus.
Dr. Shlush and his team study leukemia evolution from diagnosis to relapse. They can detect from the blood of AML patients the non-leukemic subpopulations that were ancestral to the leukemic cells and...
The main interest of the Yaniv lab is to understand the mechanisms controlling the formation of blood and lymphatic vessels during embryonic development...
Prof. Yarden addresses the effect of the ErbB family on the mobility of tumor cells and on their ability to cross tissue barriers.
A physician-scientist, Dr. Erez is working to decipher the dynamics of cellular metabolism at different disease states.